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Table of Contents

SCD Pathogenesis
SCD Genetics
SCD Biochemistry
     Hemoglobin Molecule
     Hb S Structure
     Hb S Polymerization
     RBC Sickling
SCD Epidemiology
     Prevalence & Incidence
     Morbidity & Mortality
SCD Pathology
     Disease Severity
     Clinical Aspects & Treatment
SCD Pathophysiology
     Sickled Cells
     Cellular Effects